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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs the potential risk of a possible rise in blood pressure. Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you should err on the side of caution and permit the FDA do its job and demand some investigation be done so that the public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies come in business to generate money and that they would say anything to keep people on his or her medications. Researchers found out that participants investing in this drug for the year, lost weight within one month and have kept the weight off during the entire 56 weeks of the study. Contrave is often a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which might make them more effective and safer. Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that as of right now there aren't any long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heartbeat, and really should not be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must not be used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. 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